Top Cool Boutique Hotels in San Francisco

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San Francisco, the vibrant city on the West Coast of the United States, is known for its picturesque scenery, iconic landmarks, and diverse cultural experiences. But when it comes to finding the perfect accommodation that defines the essence of this dynamic city, why settle for ordinary when you can indulge in the charm and uniqueness of cool boutique hotels? These hidden gems offer an extraordinary blend of style, character, and personalized service that will elevate your stay to unforgettable heights.

With an array of boutique hotels to choose from, each with its own distinctive personality, San Francisco presents a playground for those seeking an unconventional lodging experience. From historic buildings transformed into contemporary havens to sleek modern designs nestled in the very heart of bustling neighborhoods, these cool boutique hotels offer a refreshing departure from traditional accommodations. Step into a world where every detail is carefully curated, from the lobby's art installations to the thoughtfully designed rooms that serve as stylish sanctuaries.

Staying at a cool boutique hotel in San Francisco is not only about the aesthetics; it's also an opportunity to immerse yourself in the city's unique culture. Many of these hotels are located in trendy neighborhoods, surrounded by hip cafes, art galleries, and eclectic boutiques. You'll find yourself effortlessly blending in with the locals as you explore the vibrant streets, savoring artisanal cuisine and discovering hidden gems off the beaten path. Whether you're a foodie, an art enthusiast, or simply a traveler seeking a one-of-a-kind experience, these cool boutique hotels will become your gateway to the authentic San Francisco that lies beyond the tourist hotspots.

Embrace the spirit of San Francisco by indulging in the city's cool boutique hotels. From breathtaking views of iconic landmarks like the Golden Gate Bridge to personalized recommendations from passionate staff members who truly embody the city's hospitality, these accommodations are more than just places to rest your head at night. They are an extension of the San Francisco experience, where every moment is elevated, and every stay becomes a treasured memory. So why settle for ordinary when you can truly immerse yourself in the heart and soul of this remarkable city through its cool boutique hotels? .

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Our Top 10

(Sorted by rating & number of reviews)

1. Hotel Drisco
2. Hotel Zetta San Francisco
3. 1 Hotel San Francisco
4. Fairmont San Francisco Hotel
5. The Marker San Francisco
6. Casa Madrona Hotel And Spa
7. Hotel Adagio, Autograph Collection
8. The St. Regis San Francisco Hotel
9. The Clift Royal Sonesta Hotel
10. Hotel G San Francisco

Cool Boutique Hotels in San Francisco with Historic Charm

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San Francisco
Dec 16, 2025 - Dec 17, 2025

Hotel Drisco

9.5

Good

(46 Reviews)

+ 87 photos
Located in Pacific Heights, Hotel Drisco offers a tranquil retreat with easy access to the Presidio and Golden Gate Park. Nestled in a residential neighborhood, this cool boutique hotel is the perfect basecamp for exploring the city's natural wonders. Enjoy the cozy elegance of individually designed rooms and the warm hospitality that awaits you after a day of outdoor adventures.
Address: 2901 Pacific Avenue
Rating: Good 9.5 (46 Reviews)
Rooms: 93
Price: From 219$

Hotel Zetta San Francisco

7.8

Good

(841 Reviews)

+ 85 photos
Located in the bustling SoMa neighborhood, Hotel Zetta San Francisco offers an urban retreat with a tech-savvy twist. Combining industrial chic decor with high-tech features, this cool boutique hotel boasts a unique atmosphere. From the game room with a PlayStation wall to its connected guestrooms, Hotel Zetta redefines modern luxury accommodation.
Address: 55 5Th Street
Rating: Good 7.8 (841 Reviews)
Rooms: 116
Price: From 114$

1 Hotel San Francisco

8.6

Good

(170 Reviews)

+ 190 photos
Perched on the waterfront Embarcadero, Hotel Vitale offers stunning views of the iconic Bay Bridge and the mesmerizing San Francisco skyline. This sleek, eco-friendly hotel provides a serene oasis in the center of the city. Unwind in the rooftop spa, indulge in farm-to-table cuisine, and experience modern luxury with a focus on wellness, comfort, and sustainability.
Address: 8 Mission Street
Rating: Good 8.6 (170 Reviews)
Rooms: 200
Price: From 324$

Cool Boutique Hotels in San Francisco with Modern Luxury

For those seeking contemporary elegance and cutting-edge design, these cool boutique hotels in San Francisco deliver the ultimate in modern luxury. With sleek interiors, state-of-the-art facilities, and innovative amenities, these accommodations redefine the concept of stylish comfort in the city by the bay.

Fairmont San Francisco Hotel

8.0

Good

(1037 Reviews)

+ 647 photos
Nestled atop Nob Hill, The Fairmont San Francisco stands as a timeless icon of elegance. With its breathtaking Beaux-Arts architecture and panoramic views of the city, this legendary hotel embodies the essence of a cool boutique accommodation. Indulge in luxurious amenities, awe-inspiring interiors, and impeccable service that harkens back to the golden age of travel.
Address: 950 Mason Street
Rating: Good 8.0 (1037 Reviews)
Rooms: 591
Price: From 342$

The Marker San Francisco

7.9

Good

(423 Reviews)

+ 274 photos
Situated in the historic Pacific Heights neighborhood, The Marker San Francisco breathes new life into a turn-of-the-century landmark building. This boutique hotel exudes a vibrant bohemian vibe with its colorful interiors and eclectic artistic touches. Enjoy spacious rooms, a lively atmosphere, and proximity to famous sights like Alamo Square and Fillmore Street.
Address: 501 Geary Street
Rating: Good 7.9 (423 Reviews)
Rooms: 208
Price: From 149$

Casa Madrona Hotel And Spa

8.4

Good

(390 Reviews)

+ 120 photos
Situated in the picturesque town of Sausalito, just across the Golden Gate Bridge, Casa Madrona Hotel and Spa showcases stunning architecture and artful interiors. This cool boutique hotel features rooms designed by local artists, giving each space a unique character. Immerse yourself in art-inspired luxury and enjoy breathtaking views of the bay.
Address: 801 Bridgeway
Rating: Good 8.4 (390 Reviews)
Rooms: 63
Price: From 151$

Cool Boutique Hotels in San Francisco with Unique Themes

Step into a world of creativity and whimsy at these cool boutique hotels in San Francisco, each boasting a unique theme that guarantees an unforgettable stay. From lavish boutique hotels with theatrical decor to nature-inspired sanctuaries, these accommodations offer a captivating escape from the ordinary.

Hotel Adagio, Autograph Collection

8.3

Good

(958 Reviews)

+ 132 photos
Located in the heart of downtown, Hotel Adagio seamlessly blends historic romance with contemporary sophistication. The 1929 art deco building welcomes guests with stylish rooms adorned with modern furnishings, enhancing its cool boutique ambiance. Unwind at The Mortimer Bar and Lounge, a trendy speakeasy-inspired venue, before exploring the vibrant nearby neighborhoods.
Address: 550 Geary Street
Rating: Good 8.3 (958 Reviews)
Rooms: 171
Price: From 159$

The St. Regis San Francisco Hotel

8.9

Good

(85 Reviews)

+ 79 photos
Situated in the vibrant SoMa district, The St Regis San Francisco delights guests with its world-class dining experience. At the Michelin-starred restaurant, Quince, culinary masterpieces are crafted using seasonal ingredients. From exceptional wine pairings to impeccable service, this cool boutique hotel caters to discerning food and wine lovers.
Address: 125 Third Street
Rating: Good 8.9 (85 Reviews)
Rooms: 260
Price: From 452$

The Clift Royal Sonesta Hotel

8.5

Good

(1798 Reviews)

+ 78 photos
The Clift Royal Sonesta Hotel enchants guests with its visionary design and captivating interiors. Designed by Philippe Starck, this cool boutique hotel showcases a stunning lobby adorned with an eclectic collection of modern art and furniture. Stay in rooms featuring luxurious furnishings and experience the allure of one of San Francisco's most iconic and imaginative hotels.
Address: 495 Geary Street
Rating: Good 8.5 (1798 Reviews)
Rooms: 372
Price: From 148$

Cool Boutique Hotels in San Francisco for Food and Wine Lovers

Indulge your taste buds and immerse yourself in San Francisco's culinary scene with these cool boutique hotels that cater to food and wine lovers. From award-winning restaurants to thoughtfully curated wine programs, these accommodations offer a gastronomic experience like no other, embodying the flavors and essence of the city.

Hotel G San Francisco

8.4

Good

(538 Reviews)

+ 96 photos
Located in Union Square, Hotel G San Francisco celebrates innovation and design. The hotel's sleek interiors pay homage to the city's creative spirit, with custom furnishings and curated art pieces. Experience the vibrant energy of this cool boutique hotel and explore the nearby art galleries that make the neighborhood a cultural hub.
Address: 386 Geary Street
Rating: Good 8.4 (538 Reviews)
Rooms: 153
Price: From 111$

Cavallo Point

9.3

Good

(125 Reviews)

+ 243 photos
Nestled at the foot of the Golden Gate Bridge in Sausalito, Cavallo Point Lodge combines luxurious accommodations with a commitment to sustainability and outdoor exploration. This cool boutique hotel offers easy access to breathtaking hiking trails and outdoor activities in the Golden Gate National Recreation Area. Immerse yourself in nature while enjoying the comforts of this eco-friendly retreat.
Address: 601 Murray Circle
Rating: Good 9.3 (125 Reviews)
Rooms: 142
Price: From 300$

The Ritz-Carlton, San Francisco Hotel

9.0

Good

(435 Reviews)

+ 194 photos
Located in downtown, The Ritz-Carlton, San Francisco is not just a luxurious hotel but also a destination for culinary delights. Indulge in globally inspired cuisine at Parallel 37, where the menu showcases the freshest local ingredients. Immerse yourself in the art of fine dining and experience warm hospitality in this cool boutique hotel.
Address: 600 Stockton Street
Rating: Good 9.0 (435 Reviews)
Rooms: 336
Price: From 359$

Cool Boutique Hotels in San Francisco with Panoramic Views

Experience the breathtaking beauty of San Francisco from new heights by staying in these cool boutique hotels that offer panoramic views of the cityscape. Elevate your stay with stunning vistas, where you can marvel at iconic landmarks and soak in the vibrant energy of the bustling streets below.

Cool Boutique Hotels in San Francisco for Art and Design Enthusiasts

For those who appreciate art and design, these cool boutique hotels in San Francisco seamlessly blend creativity and hospitality. Celebrating local artists and designers, these accommodations offer an immersive experience that showcases the vibrant artistic scene of the city.

Cool Boutique Hotels in San Francisco for Outdoor Enthusiasts

Surrounded by natural beauty and outdoor adventures, these cool boutique hotels cater to outdoor enthusiasts who seek to combine their love for nature with an urban getaway. Enjoy convenient access to hiking trails, parks, and outdoor activities while savoring the comforts of stylish accommodations.