Top Choice Hotels in Columbia, Missouri

We checked thousands of reviews on and to find the best hotels for your stay
Go to Hotel List View map

Katerina Kore

Updated: 31 December 2023 · 3 min

Columbia affectionately known as CoMo, offers visitors a unique blend of Midwestern charm, cultural richness, and scenic landscapes that make it an ideal destination for travelers seeking both tranquility and adventure. Nestled in the very heart of the state, this vibrant university town is not only home to the University of Missouri but also serves as a gateway to exploring the region's lush parks, historic sites, and thriving culinary scene. For those planning a visit, selecting the right accommodation is key, and among the myriad of options, Choice Hotels in Columbia stand out for their quality, comfort, and value, making them a top choice for travelers.

Choice Hotels' portfolio in Columbia caters to a wide range of preferences and budgets, ensuring that every traveler finds a stay that suits their needs. From cozy inns that offer a home away from home atmosphere to modern hotels equipped with all the amenities necessary for a comfortable stay, Choice Hotels’ offerings are diverse. What makes these accommodations even more appealing is their strategic locations, offering easy access to the city's major attractions, including the University of Missouri campus, the MKT Trail, and the eclectic downtown area, enhancing the overall travel experience for guests.

Moreover, staying at a Choice Hotel in Columbia allows travelers to enjoy personalized service and thoughtful amenities designed to make their stay as enjoyable as possible. Guests can start their day with a complimentary breakfast before heading out to explore Columbia's art galleries, boutiques, and coffee shops, or take a nature hike in one of the nearby state parks. With recommendations and insights available at the front desk, visitors can discover hidden gems and local favorites, ensuring their trip to Columbia is memorable. Thus, whether visiting for business, leisure, or educational pursuits, the right Choice Hotel can significantly enhance your stay, making it an experience to remember.
Show more + Show less -

Our Top 6

(Sorted by rating & number of reviews)

1. Red Roof Inn Columbia, Tn
2. Holiday Inn Express Columbia, An Ihg Hotel
3. Comfort Suites
4. Super 8 By Wyndham Columbia Hotel
5. Hotel O Columbia Downtown Near I-65
6. Hampton Inn Columbia

Choice Hotels in Columbia, MO for Business Travelers

Check Availability

Columbia
Feb 24, 2026 - Feb 25, 2026

Red Roof Inn Columbia, Tn

5.7

Good

(78 Reviews)

+ 40 photos
For guests interested in exploring Columbia's historical and cultural attractions, Red Roof Inn offers a comfortable and budget-friendly base. With clean, pet-friendly rooms, it ensures a pleasant stay for all guests, including four-legged ones. Its location provides convenient access to Columbia's historical downtown, known for its beautifully preserved architecture, quaint shops, and cultural venues, allowing guests to experience the essence of Columbia.
Address: 1548 Bear Creek Pike
Rating: Good 5.7 (78 Reviews)
Rooms: 40
Price: From 68$

Holiday Inn Express Columbia, An Ihg Hotel

8.1

Good

(124 Reviews)

+ 79 photos
The Holiday Inn Express Columbia is known for its comfortable accommodations and exceptional service, making it a preferred option for business travelers. Rooms are designed with ample workspaces and free high-speed internet, ensuring productivity. The hotel is strategically located close to the Columbia Regional Airport and major business areas, providing easy access for attending meetings and corporate events. The complimentary Express Start Breakfast Bar is perfect for busy mornings, ensuring a strong start to the day.
Address: 1561 Halifax Drive
Rating: Good 8.1 (124 Reviews)
Rooms: 73
Price: From 125$

Choice Hotels in Columbia, MO for Family Vacations

Families visiting Columbia seek accommodations that are not just comfortable but also provide activities and amenities suitable for all ages. With features like swimming pools, family suites, and close proximity to Columbia's attractions, these hotels ensure a stress-free and enjoyable stay for both parents and children. The selections below stand out for their commitment to making family vacations memorable and fun.

Comfort Suites

8.2

Good

(754 Reviews)

+ 49 photos
Comfort Suites offers an appealing blend of spacious accommodations and family-friendly amenities. The suites provide ample room for families to spread out, with separate sleeping and living areas in some units. The indoor pool is a hit among children of all ages, providing a fun activity regardless of the weather. Additionally, its proximity to family attractions in Columbia, coupled with the complimentary hot breakfast, makes it a highly convenient choice for families.
Address: 1551 Bear Creek Pike
Rating: Good 8.2 (754 Reviews)
Rooms: 80
Price: From 101$

Super 8 By Wyndham Columbia Hotel

6.0

Good

(219 Reviews)

+ 68 photos
Super 8 by Wyndham Columbia offers affordable and cozy accommodations for adventure seekers on a budget. Its rooms are designed for comfort and restfulness, ensuring guests are well-rested for their outdoor excursions. Positioned close to the highway, it provides easy access to Columbia's wilderness areas and outdoor activities. With free breakfast and ample parking, it’s a great option for those spending most of their time exploring the rugged landscapes surrounding Columbia.
Address: 1554 Bear Creek Pike
Rating: Good 6.0 (219 Reviews)
Rooms: 54
Price: From 65$

Choice Hotels in Columbia, MO for Adventure Seekers

Adventure and outdoor enthusiasts exploring Columbia look for accommodations that not only provide a comfortable rest but also ease of access to the region's natural wonders and outdoor activities. These hotels situate guests perfectly to experience Columbia’s stunning surroundings and adrenaline-pumping adventures.

Hotel O Columbia Downtown Near I-65

4.5

Good

(85 Reviews)

+ 35 photos
Hotel O Columbia Downtown Near I-65 positions cultural enthusiasts in the lively heart of Columbia, providing easy access to the city's artistic and historical gems. The hotel blends comfort with convenience, featuring rooms that cater to rest and relaxation after a day of cultural exploration. Located near downtown, guests have the city's best museums, galleries, and live music venues just a short walk or drive away, making it an ideal choice for those who wish to soak up the local culture.
Address: 1504 Nashville Highway I-65 Exit 46
Rating: Good 4.5 (85 Reviews)
Rooms: 240
Price: From 127$

Hampton Inn Columbia

8.6

Good

(77 Reviews)

+ 63 photos
Families looking for comfort, convenience, and value will find the Hampton Inn Columbia to meet all their vacation needs. The hotel’s family rooms are comfortably furnished and include essential amenities like free Wi-Fi and HDTVs. With a complimentary hot breakfast and an outdoor pool, families can enjoy quality time without leaving the hotel. Its location offers easy access to Columbia’s parks and recreational activities, ensuring a well-rounded vacation experience for guests of all ages.
Address: 1551 Halifax Drive
Rating: Good 8.6 (77 Reviews)
Rooms: 68
Price: From 119$

Choice Hotels in Columbia, MO for Cultural Enthusiasts

For those drawn to the rich history and vibrant cultural scene of Columbia finding accommodation that reflects and facilitates an exploration of the local arts, music, and historical sites is essential. These hotels are more than just a place to stay; they are a comfortable base from which to immerse oneself in the local culture and vibrancy of Columbia.